Paola Perego Selected Research

IDN5174

11/2006

Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.

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Paola Perego Research Topics

Disease

57	Neoplasms (Cancer) 05/2024 - 02/2002
30	Carcinoma (Carcinomatosis) 01/2023 - 09/2002
12	Melanoma (Melanoma, Malignant) 01/2024 - 02/2002
7	Ovarian Neoplasms (Ovarian Cancer) 04/2022 - 01/2010
5	Lung Neoplasms (Lung Cancer) 05/2024 - 09/2009
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2022 - 11/2006
4	Neoplasm Metastasis (Metastasis) 01/2023 - 02/2002
4	Osteosarcoma (Osteogenic Sarcoma) 01/2014 - 12/2002
3	Glioblastoma (Glioblastoma Multiforme) 05/2021 - 03/2002
3	Multiple Myeloma 01/2019 - 11/2011
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2006 - 07/2004
2	Genomic Instability 01/2022 - 08/2008
2	Glioma (Gliomas) 05/2021 - 03/2002
2	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 01/2016
2	Breast Neoplasms (Breast Cancer) 01/2019 - 02/2014
2	Ovarian Epithelial Carcinoma 05/2015 - 01/2013
1	Inflammation (Inflammations) 04/2024
1	Mesothelioma 04/2024
1	Starvation 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Oncogene Addiction 10/2019

Drug/Important Bio-Agent (IBA)

28	Cisplatin (Platino)FDA LinkGeneric 05/2024 - 09/2002
16	PlatinumIBA 01/2022 - 02/2002
8	Antineoplastic Agents (Antineoplastics)IBA 01/2022 - 11/2010
7	Drug CombinationsIBA 05/2021 - 05/2005
6	Phosphotransferases (Kinase)IBA 01/2024 - 01/2013
6	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022 - 07/2008
6	Histone Deacetylase InhibitorsIBA 01/2020 - 11/2008
5	ST 1481 (Gimatecan)IBA 04/2008 - 12/2002
4	VemurafenibIBA 01/2023 - 12/2011
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 08/2008
4	EnzymesIBA 01/2022 - 02/2002
4	Platinum Compounds (Compounds, Platinum)IBA 11/2016 - 01/2006
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2016 - 09/2006
4	CamptothecinIBA 03/2010 - 12/2002
3	DNA (Deoxyribonucleic Acid)IBA 04/2022 - 02/2010
3	UbiquitinIBA 01/2022 - 01/2013
3	Histone Deacetylases (Histone Deacetylase)IBA 01/2020 - 04/2012
3	ErbB Receptors (EGF Receptor)IBA 10/2019 - 03/2008
3	Tyrosine Kinase InhibitorsIBA 10/2019 - 02/2014
3	tyrosine receptor (receptor, tyrosine)IBA 04/2019 - 01/2013
3	IntegrinsIBA 04/2019 - 08/2012
3	Bortezomib (Velcade)FDA Link 01/2019 - 11/2011
3	LigandsIBA 06/2014 - 03/2006
3	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2012 - 04/2003
3	Topotecan (Hycamtin)FDA LinkGeneric 11/2006 - 12/2002
2	LipidsIBA 01/2024 - 01/2022
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2024 - 01/2020
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2024 - 01/2022
2	Peptides (Polypeptides)IBA 01/2023 - 07/2022
2	Ubiquitin-Specific ProteasesIBA 01/2022 - 01/2022
2	CurcuminIBA 01/2022 - 01/2022
2	Temozolomide (Temodar)FDA LinkGeneric 05/2021 - 06/2014
2	Sunitinib (Sutent)FDA Link 04/2019 - 02/2014
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 07/2010
2	Messenger RNA (mRNA)IBA 03/2016 - 03/2015
2	Small Interfering RNA (siRNA)IBA 03/2016 - 12/2011
2	Epithelial Cell Adhesion MoleculeIBA 09/2015 - 09/2009
2	Caspase 3 (Caspase-3)IBA 02/2014 - 01/2014
2	CytokinesIBA 01/2014 - 01/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014 - 03/2006
2	multidrug resistance-associated protein 1IBA 01/2013 - 04/2010
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2013 - 12/2012
2	Proteasome InhibitorsIBA 01/2013 - 08/2012
2	OligodeoxyribonucleotidesIBA 01/2010 - 04/2008
2	CPG-oligonucleotideIBA 01/2010 - 04/2008
2	Topoisomerase I InhibitorsIBA 10/2008 - 03/2002
2	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 10/2006 - 02/2002
2	BBR 3464 (BBR3464)IBA 01/2006 - 07/2003
1	AsbestosIBA 04/2024
1	Oleic Acid (Oleate)IBA 01/2024
1	KisspeptinsIBA 01/2023
1	EstersIBA 01/2023
1	Kisspeptin-1 ReceptorsIBA 01/2023
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2023
1	Biomarkers (Surrogate Marker)IBA 07/2022
1	Conditioned Culture MediaIBA 07/2022
1	avasimibeIBA 01/2022
1	CholesterolIBA 01/2022
1	Therapeutic UsesIBA 01/2022
1	Proto-Oncogene Proteins B-rafIBA 01/2022
1	caffeic acid phenethyl esterIBA 01/2022
1	Eukaryotic Initiation Factor-4EIBA 01/2022
1	Deubiquitinating EnzymesIBA 01/2022
1	Peptide Hydrolases (Proteases)FDA Link 01/2022
1	Glutamate Receptors (Glutamate Receptor)IBA 05/2021
1	Orlistat (Xenical)FDA Link 05/2021
1	perampanelIBA 05/2021
1	AZD 6244IBA 01/2020
1	ricolinostatIBA 01/2020
1	Histone Deacetylase 6IBA 01/2020
1	Mitogen-Activated Protein KinasesIBA 01/2020
1	osimertinibIBA 10/2019
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 04/2019
1	VLX1570IBA 01/2019
1	ProteomeIBA 01/2019
1	PorphyrinsIBA 01/2019

Therapy/Procedure

17	Therapeutics 01/2024 - 03/2002
4	Drug Therapy (Chemotherapy) 01/2019 - 05/2005
1	Castration 01/2020